Recent Postings

Given the risks associated with Entresto, Public Citizen’s Health Research Group has classified it as Limited Use, to be used only in adults with heart failure with reduced ejection fraction.

In his editor’s column, Dr. Carome explains how the FDA’s reliance on user fees from prescription drug manufacturers has resulted in corporate capture of the agency.

Learn about new research showing that increased rates of overdose and mental health crises persist during the second year after initiation of opioid tapering among patients taking stable, long-term, high-dose prescriptions of these medications.

Patients taking the drug sotalol (BETAPACE, BETAPACE AF, SORINE, SOTYLIZE) should be aware that it has clinically important and potentially dangerous interactions with many other prescription medications.

Age-related macular degeneration is a leading cause of vision loss in older adults. Find out which patients with this condition can benefit from a combination of specific dietary supplements known as AREDS2.

Given the serious risks of opioids, it is critical to dispose of any unused doses as soon as there is no longer a medical need for them. Learn how to do so safely by following the recommendations of the FDA.

The need for a rule that would allow generic-drug companies to promptly update safety warnings in their product labeling is more critical than ever given that approximately 90% of all prescriptions dispensed in the U.S. are generic medications and the reality that new information about serious risks often comes to light after generic versions of a drug come on the market.

Learn about the U.S. Preventive Services Task Force’s (USPSTF’s) updated recommendations regarding the use of daily aspirin to prevent heart attacks and strokes in patients without signs, symptoms or history of cardiovascular disease.

Patients taking fluvoxamine (LUVOX), a selective serotonin reuptake inhibitor (SSRI), should be aware that it has clinically important interactions with many other prescription and over-the-counter medications.

Recently published research provides the strongest evidence to date that erectile dysfunction drugs increase the risk of rare, serious adverse ocular events that can lead to vision loss.

In this month’s news brief, we discuss a recently published study showing that in 2020, melatonin became the most frequently ingested substance among children and young adults reported to poison control centers in the U.S.

Data from a recently published large observational study confirm that myocarditis and pericarditis are rare but usually reversible adverse effects associated with COVID-19 messenger RNA vaccination.

In his editor’s column, Dr. Carome discusses the major provisions of the recently enacted Inflation Reduction Act of 2022 that will help make prescription drugs more affordable for Medicare patients.

Learn about the numerous prescription medications and some over-the-counter drugs that can cause psychotic symptoms, including hallucinations.

New research reveals that use of certain acetaminophen products that contain significant amounts of sodium is associated with an increased risk of developing cardiovascular disease and high blood pressure.

Patients taking the commonly prescribed diuretic spironolactone should be aware that it has clinically important interactions with many other commonly used prescription and over-the-counter medications.