Beclomethasone inhaled steroid (QVAR REDIHALER), fluticasone inhaled steroid (FLOVENT DISKUS, FLOVENT HFA) and triamcinolone inhalation (AZMACORT AEROSOL CANISTER) are steroids that have similar efficacy when inhaled., When used routinely, steroids inhaled by mouth prevent or reduce inflammation due to asthma. These drugs are not bronchodilators (drugs that open airways) and are not intended to treat acute asthma attacks or status asthmaticus. However, they do reduce inflammation,...
Beclomethasone inhaled steroid (QVAR REDIHALER), fluticasone inhaled steroid (FLOVENT DISKUS, FLOVENT HFA) and triamcinolone inhalation (AZMACORT AEROSOL CANISTER) are steroids that have similar efficacy when inhaled., When used routinely, steroids inhaled by mouth prevent or reduce inflammation due to asthma. These drugs are not bronchodilators (drugs that open airways) and are not intended to treat acute asthma attacks or status asthmaticus. However, they do reduce inflammation, improve lung function and reduce the number of acute asthma attacks.
Asthma is a progressive disease that can develop at any age. Lung function declines and irreversible obstruction of the airways can occur. Diseases of the nose or sinuses and viral infections may worsen asthma. Drugs control symptoms of asthma (shortness of breath, chest tightness, wheezing and coughing), but they do not cure the disease itself.
Steroids are available as aerosols or as dry powder to be inhaled through an accompanying device. Time for initial improvement varies from one to 14 days; full benefits take several weeks to months to occur. Proper technique in using the device delivering the steroid is important to the effectiveness of inhalers.
Patients discontinuing use of oral steroids need to taper down the dose slowly and carefully under the supervision of a physician because it takes several months for adrenal function to recover. Deaths from adrenal insufficiency have occurred when the drug was tapered too quickly. Patients should be especially watchful if they experience trauma, surgery, infections or gastroenteritis while weaning off the drug.
Although inhaled steroids reduce the likelihood of systemic effects, the risks are not eliminated.
Steroids can suppress natural adrenal gland hormone production and potentially change bone mineral density., Adrenal insufficiency can cause low blood sugar, unconsciousness, convulsions, coma or death. This also can occur during fasting or if steroids are stopped abruptly.
A detachment of the retina called chorioretinopathy has been associated with steroid inhalers, especially in women. There have been reports of cataracts in both children and adults using inhaled beclomethasone.
A rare disease called Churg-Strauss syndrome, a condition in which blood vessels become inflamed, has been associated with both systemic and inhaled steroids.
Steroids can slow growth and development in children. The safety and effectiveness of steroids in children under three months of age have not been established.
Steroids also can make you more susceptible to infections, which can lead to fungal infection of the mouth, throat and voice box called candidiasis or aspergillosis. The risk increases with higher doses, and may be higher with fluticasone., Patients can help reduce this risk by avoiding swallowing after rinsing their mouths. Children or adults who have not had chicken pox or measles should avoid exposure to these diseases.
The most frequently reported adverse effect associated with inhaled corticosteroid use in children with asthma is behavior alteration, according to researchers from the Netherlands. Researchers have received reports of behavioral changes in children associated with the use of inhaled fluticasone propionate or salmeterol/fluticasone propionate., The use of intranasal or inhaled corticosteroids appears to be associated with psychiatric disorders.,
There have been 18 reports of skin bruising associated with the use of inhaled and/or intranasal fluticasone products.
In onetrial comparing inhaled triamcinolone with a placebo (a pill with no medicinal effect), patients using triamcinolone experienced more skin adverse effects, such as bruising and delayed healing.