Search results below include Worst Pills, Best Pills Newsletter Articles where your
selected drug is a secondary subject of discussion.
February 2021
In this article, we review four postmarketing studies Purdue Pharma submitted to the FDA that evaluated the alleged abuse-deterrent properties of the company’s reformulated OxyContin and the agency’s independent assessment of the studies’ results. The data failed to show any meaningful reductions in overall opioid abuse or overdoses since the reformulated Oxycontin was approved in 2010.
July 2019
Too often, senior executives of leading pharmaceutical companies that engage in illegal marketing of drugs and other serious crimes escape criminal prosecution. But this was not the case for the billionaire founder of Insys Therapeutics.
February 2019
In his editor’s column, Dr. Michael Carome slams the FDA for its reckless approval of a dangerous new opioid that will be marketed under the brand name Dsuvia.
May 2016
For various reasons, many prescribed medications go unused. Such leftover medications can pose a hazard to family members, especially young children, and the environment. Find out the best ways to safely dispose of unused prescription medications.
March 2013
What kind of headache is not relieved by pain medications but actually caused by their frequent overuse? The article describes which painkillers can cause medication overuse headaches (MOH) when used too frequently over specified durations of time.
June 2011
This article lists 355 drugs with names that are often confused with similar-sounding drug names. Find out what you can do to prevent getting the wrong drug.
March 2009
The article lists 57 different drugs that can cause dementia if used. This can be even more problematic if more than one of these drugs is being taken. These drugs are only one class of drugs that can cause mental deterioration and next month's issue will discuss additional drugs that can also impair thinking.
August 2008
The article discusses 273 drugs that can have harmful interactions with alcohol. Also reviewed are several ways in which these harmful interactions can occur:
1/ Medications Can Increase Alcohol Blood Levels
2/ Additive effects of medications and alcohol. One of the best- known drug-alcohol interactions is when alcohol, a depressant, is taken with other sedative medications, and excessive sedation or depression of respiration can occur
3/Alcohol can increase the blood levels of some medications leading to toxicity of these drugs.
4/ Alcohol also can reduce blood levels of some medications causing them to be less effective.
Although some of the interactions between alcohol and medications mainly occur in people who drink heavily (three or more drinks on one occasion), many of these interactions may occur with much lower amounts of alcohol use, such as one to two drinks on an occasion.
We strongly urge you to tell your physicians and other health care providers how much alcohol you are drinking so they can effectively assess the risks and advise you about the safe use of alcohol and medications.
May 2007
A few months ago the FDA warned about the potential of methadone - when used to treat pain - to cause life-threatening breathing problems and heart rhythm disturbances. When it made this safety announcement, however, the FDA negligently failed to point out that they had recommended a drastic reduction in the starting dose for pain to prevent some of these life-threatening adverse reactions. The new recommended starting dose is more than a 2.5 fold reduction in the dosage for the initial treatment of pain. Symptoms of overdose with the older, higher doses are discussed in the article.
February 2007
Deaths, cardiac and respiratory, have been reported during initiation and conversion of pain patients to methadone treatment from treatment with other opioid agonists. Because methadone has some of the effects of other narcotics, do not stop the drug without consulting the prescriber because of the possibility of serious and uncomfortable withdrawal symptoms.
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