naloxone (EVZIO, KLOXXADO, NARCAN, REVIVE, REXTOVY, RIVIVE, ZIMHI)

Opioid Overdose Antidotes to Avoid: High-Dose Naloxone and Nalmefene Nasal Sprays
September 2024
The FDA recently approved two additional drugs for opioid use disorder, both of which are nasal spray formulations. One drug is high-dose naloxone and the other is a derivative of naloxone known as nalmefene (OPVEE). Naloxone nasal spray, which is sold over the counter, is a safer choice. The newer formulations are more expensive, usually no more effective and may trigger longer and more intense withdrawal.

New Study Makes Case for Increased Access to the Opioid Overdose Antidote Naloxone
January 2020
Learn about the results of new research suggesting that implementation of laws expanding naloxone access by authorizing pharmacists to dispense the drug without a prescription may result in fewer opioid-related deaths.

Making Opioid Overdose Antidote Affordable Would Save Lives
July 2018
In his editor’s column, Dr. Michael Carome discusses a rarely used authority of the federal government that would lower the price for the opioid-overdose antidote naloxone and save lives.