Worst Pills, Best Pills

An expert, independent second opinion on more than 1,800 prescription drugs, over-the-counter medications, and supplements

phenobarbital (LUMINAL, SOLFOTON)


DISEASE AND DRUG FAMILY INFORMATION

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion.

Opioids
Most of the time when someone is able to swallow, they should first try a non-opioid drug such as aspirin taken by mouth. If aspirin alone is not effective, it can be combined with an opioid, such as codeine. These two drugs work in different ways, and when they are used together, they generally relieve pain that would otherwise require a higher dose of an opioid, while causing fewer adverse effects.

DRUG AND DIETARY SUPPLEMENT PROFILES

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include Drug and Dietary Supplement Profiles where your selected drug is a primary subject of discussion.


WORST PILLS, BEST PILLS NEWSLETTER ARTICLES

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion.

Important Drug Interactions for the Seizure Drug Carbamazepine
March 2021
Patients taking the commonly prescribed epilepsy drug carbamazepine (CARBATROL, EPITOL, EQUETRO, TEGRETOL, TERIL) should be aware that it has clinically important interactions with numerous other prescription and over-the-counter medications.
Important Drug Interactions for the Seizure Drug Phenytoin
September 2019
Patients taking the commonly prescribed epilepsy drug phenytoin (DILANTIN, PHENYTEK), one of the oldest epilepsy drugs, should be aware that it has clinically impor¬tant interactions with many other prescription and over-the-counter medications. Some of these interactions can lead to phenytoin toxicity, and others can lead to ineffective seizure control.
Aripiprazole (ABILIFY) Drug Interactions
September 2018
Read about the more than two dozen medications that can have clinically important interactions with aripiprazole, one of the widely used newer atypical antipsychotic drugs that is approved by the FDA for treatment of several disorders including schizophrenia, bipolar disorder and depression.
Quality of Drug Prescribing
March 2011
The article reviews a study on the potentially dangerous, inappropriate prescribing of 77 drugs that pose a high risk to older adults. Of the 67 of these drugs that we had previously reviewed in Worst, Pills, Best Pills News, we had classified 60 (90 percent) of them as “Do Not Use,” and the other seven as "Limited Use."
Corticosteroid Drug Interactions
November 2010
This article discusses 36 drugs that, when used by people also using a corticosteroid, can either cause toxic interactions with the steroid or decrease the steroid's effectiveness.
Aripiprazole (ABILIFY) Drug Interactions
April 2010
The article lists 53 drugs that can interact with the psychiatric drug ABILIFY to either increase the amount in the body, which can lead to toxicity, or decrease the amount rendering the drug less effective.
Digoxin Drug Interactions
March 2010
The article lists 35 different interacting drugs that can either increase blood levels of digoxin, leading to the serious problem of digitalis toxicity or decrease blood levels, causing the drug to be less effective.
Quetiapine (SEROQUEL) Interactions With Other Drugs
February 2010
Quetiapine (SEROQUEL) can interact with 26 different drugs, increasing its blood levels and causing dangerous side effects such as slowed breathing, dizziness and fainting. The article also lists 10 other interacting drugs that can result in lower blood levels, rendering the drug less effective.
Oxycodone: Be Careful What You Take With It
September 2009
The article lists 24 drugs that can increase the toxicity of oxycodone if taken together with the drug and 11 other drugs that can weaken its effectiveness as a painkiller if they are simutaneously used.
Tizanidine: Watch Out for Drugs Interacting With This Muscle Relaxant
October 2008
Tizanidine (ZANAFLEX) is a muscle relaxant for which more than 3.8 million prescriptions were filled in the U.S. last year. The article lists more than 64 drugs with which it can have dangerous interactions resulting in excess sedation, difficulty breathing or dangerously low blood pressure that can result in falling.
Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease
April 2008
This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.
Drug Induced Psychiatric Symptoms
October 2002
This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.