Worst Pills, Best Pills

An expert, independent second opinion on more than 1,800 prescription drugs, over-the-counter medications, and supplements



Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion.

Commonly Used Oral Drugs That Can Cause Eye Problems; Second of a Two-Part Series
February 2020
In this second of a two-part series, we review some of the many commonly prescribed medications that can damage your eyes and the steps that you can take to protect yourself from these adverse effects. The first part in this series appeared in our December 2019 issue.
An Updated Look at the Treatments for Rosacea
September 2019
Rosacea is a chronic skin condition affecting 13 million Americans. Find out steps to take to prevent symptom flare-ups and learn which topical drug therapies are most effective and safest for treating this condition.
Drugs That Cause Sun-Related Skin Reactions
July 2016
Summer is a terrific time for healthy outdoor activities, such as walking, hiking, biking and swim¬ming. But for an unlucky few, certain medications can lead to adverse skin reactions following exposure to the sun. Find out whether you are at risk and how to protect yourself.
Drug-Induced Hair Loss
July 2016
For most people with hair loss, the condition usually is age-related or due to the genes they inherited from their parents. But for some patients, the cause of the problem can be found in the medicine cabinet. Learn about some commonly used medications that can cause hair loss.
Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease
April 2008
This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.
The Inappropriate Prescribing of the Acne Drug Isotretinoin (ACCUTANE) Continues
April 2004
Public Citizen’s Health Research Group has been warning the FDA about the risks of birth defects and mental retardation for fetuses exposed to isotretinoin (ACCUTANE) for over 20 years. This article contains the history of these efforts and warns that you or your children should use isotretinoin only in the case of severe recalcitrant nodular acne after other safer acne treatments have been tried and failed. Exposure of an unborn fetus to isotretinoin is a serious adverse event and should be reported directly to the FDA Med Watch Program along with other adverse reactions.
The Tetracycline Antibiotic Minocycline (MINOCIN) and Benign Intracranial Hypertension
May 2003
Benign intracranial hypertension is, in fact, not benign at all. It is also known as pseudotumor cerebri and involves a persistent rise in cerebrospinal fluid pressure. This reaction is characterized by headache, nausea, vomiting and papilledema (a sign of increased pressure within the central nervous system) with partial paralysis of a nerve that controls eye movement and some facial muscles (sixth cranial nerve palsy). If you are taking minocycline or another tetracycline and develop a persistent unexplained headache, this should be reported to the prescribing physician immediately.
Drug Induced Psychiatric Symptoms (Part 2)
November 2002
This is the second of a two-part series on drug-induced psychiatric symptoms that began in last month’s Worst Pills, Best Pills News. The information is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Article lists drugs and adverse effects.
FDA’s ‘New’ Program to Prevent Birth Defects Caused By Acne Drug Isotretinoin (ACCUTANE) Is Powerless
December 2001
The Food and Drug Administration (FDA) announced a “new” program on November 1, 2001 to prevent pregnancies and eliminate fetal exposure in women taking the acne drug isotretinoin (ACCUTANE) produced by Roche Laboratories of Nutley, New Jersey. The stated goals of the program are that: 1) no woman should begin isotretinoin treatment if she is pregnant; and 2) no pregnancies should occur while a woman is on the drug. You or your children should only use isotretinoin in the case of severe recalcitrant nodular acne after other safer acne treatments have been tried and failed.


Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion.

Testimony before FDA Advisory Committee on Accutane. It should be removed from the market and prescribed only under very limited and controlled conditions. (HRG Publication #1691)
The acne drug Accutane, which causes birth defects and life-threatening adverse events, should be removed from the market and prescribed only under very limited and controlled conditions. Testimony before FDA Advisory Committee (HRG Publication #1691)
Comments Before the Food and Drug Association's Dermatologic and Ophthalmic Drugs Advisory Committee meeting on Isotretinoin (Accutane). (HRG Publication #1537)
Where industry interests have been at stake, the FDA has been innovative in interpreting the Food, Drug and Cosmetic Act to get drugs such as clozapine, thalidomide and dofetilide on the market. It is time for the agency use the same creativity to protect the public's safety.