Worst Pills, Best Pills

An expert, independent second opinion on more than 1,800 prescription drugs, over-the-counter medications, and supplements



Search results below include E-Alerts where your selected drug is a primary subject of discussion.


Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion.

Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease
April 2008
This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.
The FDA Finally Bans Ephedra
February 2004
Once again, Worst Pills, Best Pills readers were warned about the dangers of a drug well before — in this case two and one-half years before — the government got around to a ban.
Review of Adverse Effects and Contraindications of Various Dietary Supplements Used for Weight Loss
December 2002
Ephedra, or ma huang, the natural form of the stimulant ephedrine, the most infamous and dangerous drug found in dietary supplements sold for weight loss, is at last beginning to receive the negative notoriety it deserves. Ephedra causes heart attacks and strokes because of its ability to raise blood pressure and heart rate. Article discusses the risk of other dietary supplements.


Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion.

FDA Neglecting Its Responsibility to Protect Children From Risky, Ineffective Cough and Cold Medicines
By simply warning parents not to administer over-the-counter cough and cold remedies to children under the age of 2, the U.S. Food and Drug Administration (FDA) has failed to properly address the glaring risks presented by this category of drugs, Public Citizen said today.
Children Under 12 Should Not Be Given Cough, Cold Medications, Public Citizen Tells FDA
Children under the age of 12 should not be given over-the-counter (OTC) cough and cold medicines, and remedies aimed specifically at children should be removed from the U.S. market, Public Citizen said today in testimony before the Food and Drug Administration (FDA).
Letter to HHS Secretary Tommy Thompson urging him to direct the FDA to open a criminal investigation of Metabolife (HRG Publication #1635)
This letter strongly urges you to direct FDA Chief Counsel Dan Troy to agree that a criminal investigation of Metabolife be opened, as requested in a July 1, 2002, letter he was sent from Eugene M. Thirolf, Director, Office of Consumer Litigation, U.S. Department of Justice (DOJ). In that letter, the DOJ official states that Michael Ellis, the President of Metabolife, one of the nation’s largest producers of ephedrine-based dietary supplements, may have made false statements to the FDA.
Statement before the National Academy of Sciences on the Framework for Evaluating the Safety of Dietary Supplements (HRG Publication #1594)
Since at the heart of this problem is the irrational legal distinction that has been made between those pharmacologically active chemicals which are regulated as prescription or over-the-counter drugs and those which others call dietary supplements which I call drug supplements, eventually the same standards for safety and effectiveness must be adopted.
Petition to the Food and Drug Administration (FDA) requesting the ban of production and sale of dietary supplements containing ephedrine alkaloids. (HRG Publication #1590)
The Public Citizen Health Research Group, petitions the Food and Drug Administration (FDA) to ban the production and sale of dietary supplements containing ephedrine alkaloids. These dietary supplements include, but are not limited to, those containing ephedra, ephedra extract, and ma-huang. The grounds for FDA action are that these products present a significant or unreasonable risk of illness or injury under conditions of use suggested or recommended in the labeling
Testimony before the House of Representatives Committee on Government Reform Hearing on Dietary Supplements. (HRG Publication #1560)
When the first member of this committee or of Congress or their families, has a stroke, a fatal cardiac arrhythmia, or some other life-threatening adverse reaction to dietary supplements, perhaps there will be a belated reconsideration of the damage done by DSHEA. The law will then either be significantly modified or repealed so that pre-marketing safety and efficacy testing become the preferable alternative to post-marketing human experimentation.
Comments on the Department of Health and Human Services' Inspector General’s Study of Adverse Event Reporting for Dietary Supplements. (HRG Publication #1568)
We are very concerned about the dangerous inadequacy of FDA's adverse reaction reporting system for dietary supplements---wherein, for 1994 through 1999, the number of such reports filed with the American Association of Poison Control Centers (AAPCC) was 35,400, more than ten times higher than the approximately 3,000 reported to the FDA.
Letter to the Food and Drug Administration regarding their final regulations on dietary supplements and their definition of adverse effects of pregnancy. (HRG Publication #1507)
Now, the same agency seems to have thrown caution to the wind and appears willing to endanger unborn babies by pretending that medical conditions such as morning sickness and edema of pregnancy are not diseases, thereby allowing the marketing of dietary supplements/herbals that have not been tested for safety.