Worst Pills, Best Pills

An expert, independent second opinion on more than 1,800 prescription drugs, over-the-counter medications, and supplements

digoxin (LANOXIN)


DRUG AND DIETARY SUPPLEMENT PROFILES

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include Drug and Dietary Supplement Profiles where your selected drug is a primary subject of discussion.


WORST PILLS, BEST PILLS NEWSLETTER ARTICLES

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion.

Important Drug Interactions for the Stomach-Acid–Suppressing Drug Rabeprazole (ACIPHEX)
June 2023
Patients taking the stomach-acid-suppressing drug rabeprazole (ACIPHEX) should be aware that it has clinically important interactions with many other prescription medications. Public Citizen’s Health Research Group has designated rabeprazole, a protein pump inhibitor, as Limited Use.
Important Drug Interactions for the Hypertension Drug Felodipine
April 2023
Patients taking the commonly prescribed calcium channel blocker felodipine should be aware that it has clinically important interactions with many other prescription medications as well as the dietary supplement St. John’s wort.
Drug and Food Interactions for the Thyroid Medication Levothyroxine
March 2023
Patients taking the widely prescribed hypothyroidism drug levothyroxine should be aware that it has clinically important interactions with many other prescription and over-the-counter medications, dietary supplements and even certain foods.
Important Drug Interactions for Sotalol
January 2023
Patients taking the drug sotalol (BETAPACE, BETAPACE AF, SORINE, SOTYLIZE) should be aware that it has clinically important and potentially dangerous interactions with many other prescription medications.
Drug-Induced Psychotic Symptoms, Including Hallucinations
November 2022
Learn about the numerous prescription medications and some over-the-counter drugs that can cause psychotic symptoms, including hallucinations.
Important Drug Interactions for the Combination Antiviral COVID-19 Drug PAXLOVID
August 2022
Patients taking the oral combination antiviral drug PAXLOVID (nirmatrelvir and ritonavir), which is used to treat COVID-19, should be aware that it has clinically important and potentially dangerous interactions with many other prescription medications.
Important Drug Interactions for Quinidine
June 2022
Patients taking the drug quinidine should be aware that it has clinically important and potentially dangerous interactions with many other prescription medications.
Medications That Cause Diarrhea
March 2022
More than 700 medications have been implicated in inducing diarrhea, accounting for nearly 7% of all adverse drug events. Knowing which medications prescribed or recommended by your doctor cause diarrhea will allow you to take steps to prevent or minimize this common adverse drug effect.
Why You Should Avoid the Herbal Supplement St. John’s Wort
December 2021
Learn why we have designated St. John’s wort, an herbal dietary supplement that is commonly available in capsules, tablets or teas, as Do Not Use.
Important Drug Interactions for the Antifungal Drug Itraconazole
November 2021
Patients taking the oral antifungal drug itraconazole (SPORANOX, TOLSURA) should be aware that it has clinically important interactions with many other prescription medications that can affect the safety or effectiveness of itraconazole or the interacting drugs.
Important Drug Interactions for the Stomach-Acid–Suppressing Drugs Lansoprazole and Dexlansoprazole
October 2021
Patients taking the commonly used stomach-acid–suppressing drugs lansoprazole (PREVACID, PREVACID 24 HR) and dexlansoprazole (DEXILANT) should be aware that these drugs have clinically important interactions with many other prescription medications.
Important Drug Interactions for the Hypertension and Angina Drug Nifedipine
August 2021
Patients taking the widely prescribed calcium channel blocker nifedipine (PROCARDIA, PROCARDIA XL) should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Abnormal Heart Rhythm Drug Amiodarone
July 2021
Patients taking the commonly prescribed abnormal heart rhythm drug amiodarone should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Antibiotic Erythromycin
June 2021
Patients taking the commonly prescribed antibiotic erythromycin should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for Cholesterol-Lowering Drug Atorvastatin (LIPITOR)
April 2021
Patients taking the commonly prescribed drug atorvastatin, which is a member of the statin family of cholesterol-lowering drugs, should be aware that it has clinically important interactions with many other prescription medications.
Drugs That Cause Magnesium Deficiency
February 2021
Magnesium deficiency, due to either inadequate dietary intake, impaired intestinal absorption or excessive urinary loss of the mineral, results in low blood magnesium levels — a condition known as hypomagnesemia — and a wide range of adverse health effects. Importantly, many commonly used drugs also can cause magnesium depletion.
Important Drug Interactions for the Calcium Channel Blocker Diltiazem
December 2020
Patients taking the widely prescribed calcium channel blocker diltiazem (CARDIZEM, CARTIA XT, TAZTIA XT, TIAZAC) should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Stomach-Acid–Suppressing Drug Omeprazole
October 2020
Patients taking the commonly used stomach-acid–suppressing drug omeprazole should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Antibiotic Azithromycin
July 2020
Patients taking the commonly prescribed antibiotic azithromycin (ZITHROMAX) should be aware that it has clinically important dangerous interactions with many other prescription medications.
Important Drug Interactions for Cholesterol-Lowering Drug Simvastatin
June 2020
Patients taking the commonly prescribed cholesterol-lowering drug simvastatin (FLOLIPID, VYTORIN, ZOCOR) should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Antibiotic Clarithromycin
April 2020
Patients taking the commonly prescribed antibiotic clarithromycin (BIAXIN XL) should be aware that it has clinically important interactions with many other prescription medications.
Important Drug Interactions for the Calcium Channel Blocker Verapamil
March 2020
Patients taking the widely prescribed calcium channel blocker verapamil — which is used to treat high blood pressure, coronary artery disease and certain abnormal heart rhythms — should be aware that it has clinically important interactions with many other prescription medications.
Commonly Used Oral Drugs That Can Cause Eye Problems; Second of a Two-Part Series
February 2020
In this second of a two-part series, we review some of the many commonly prescribed medications that can damage your eyes and the steps that you can take to protect yourself from these adverse effects. The first part in this series appeared in our December 2019 issue.
Important Drug Interactions for the Seizure Drug Phenytoin
September 2019
Patients taking the commonly prescribed epilepsy drug phenytoin (DILANTIN, PHENYTEK), one of the oldest epilepsy drugs, should be aware that it has clinically impor¬tant interactions with many other prescription and over-the-counter medications. Some of these interactions can lead to phenytoin toxicity, and others can lead to ineffective seizure control.
For Some Drugs, Crushing Tablets or Opening Capsules Can Yield Fatal Consequences
June 2019
Patients who have difficulty swallowing pills will sometimes crush tablets or open capsules and sprinkle the resulting powder, fragments or granules into food or liquids. Other patients will resort to chewing their pills before swallowing. Find out the dangers posed by taking such measures.
Colchicine Interactions with Other Drugs Can Be Life-Threatening
May 2019
Read about the many prescription medications that can interact in dangerous ways with colchicine, a commonly used drug for treatment of acute gout attacks.
Medications That Induce Breast Enlargement in Men
May 2019
For men, abnormally large breasts can be distressing and embarrassing. Find out about the numerous drugs that can cause breast enlargement in men.
Potentially Dangerous Digoxin Drug Interactions
November 2018
Read about the numerous medications that can interact with digoxin, a drug commonly prescribed for heart failure and atrial fibrillation. These interactions can result in either digoxin toxicity or decreased digoxin effectiveness depending on the other drug being used concomitantly.
Drug Treatments for Chronic Heart Failure
January 2016
For the approximately 5 million Americans suffering from chronic heart failure, there is a wide array of lifesaving drug treatments. Find out our take on the most recent expert guidelines for treating this disease.
With Some Drugs, Crushing Tablets Or Opening Capsules Could Have Fatal Consequences
February 2015
Patients who have difficulty swallowing pills will sometimes crush tablets or open capsules and sprinkle the resulting powder, fragments or granules into food or liquids. Other patients will resort to chewing their pills before swallowing. Find out the dangers posed by taking such measures.
Digoxin Drug Interactions
March 2010
The article lists 35 different interacting drugs that can either increase blood levels of digoxin, leading to the serious problem of digitalis toxicity or decrease blood levels, causing the drug to be less effective.
Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia
April 2009
This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
Update on Drugs that Can Cause High Blood Potassium
December 2008
This article lists 68 drugs that can cause high blood potassium (hyperkalemia) that can result in nausea, fatigue, muscle weakness or tingling sensations, as well as heart abnormalities (showing up as an abnormal electrocardiogram). In some cases it can be fatal. If you are taking any of these drugs, be especially careful if you have diabetes or kidney disease. If so, you are at increased risk, and your doctor will have to weigh the risk of giving you these drugs. Also, the older you are, the more likely you are to develop hyperkalemia. Also, make sure you are receiving appropriate laboratory monitoring.
Colchicine Interactions with Other Drugs Can Be Life-Threatening
December 2008
This article lists 27 drugs that can have life-threatening interactions with the widely-used gout drug, colchicine, resulting in dangerously elevated levels of colchicine. Too much colchicine in the body leads to toxicity such as fever, vomiting, diarrhea, abdominal pain and muscle pains. Even worse, it can impair the bone marrow’s ability to make red and white blood cells, causing severe anemia and dangerously low numbers of white blood cells. When the number of white blood cells is reduced, your body may have difficulty fighting infections. Most people who have died from colchicine toxicity have had bone marrow toxicity or had preexisting kidney problems. Every patient on colchicine — whether on other drugs or not — should be alert for evidence of colchicine toxicity as described above.
Review of Adverse Effects and Contraindications of Various Dietary Supplements Used for Weight Loss
December 2002
Ephedra, or ma huang, the natural form of the stimulant ephedrine, the most infamous and dangerous drug found in dietary supplements sold for weight loss, is at last beginning to receive the negative notoriety it deserves. Ephedra causes heart attacks and strokes because of its ability to raise blood pressure and heart rate. Article discusses the risk of other dietary supplements.
Drug Induced Psychiatric Symptoms (Part 2)
November 2002
This is the second of a two-part series on drug-induced psychiatric symptoms that began in last month’s Worst Pills, Best Pills News. The information is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Article lists drugs and adverse effects.