Worst Pills, Best Pills

An expert, independent second opinion on more than 1,800 prescription drugs, over-the-counter medications, and supplements



Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion.

Allergy and Hayfever
If you suffer from an itchy and runny nose, watery eyes, sneezing, and a tickle in the back of your throat, then you probably have an allergy. An allergy means a hypersensitivity to a particular substance called an allergen. Hypersensitivity means that the body’s immune system, which defends against infection, disease, and foreign bodies, reacts inappropriately to the allergen. Examples of common allergens are pollen, mold, ragweed, dust, feathers, cat hair, makeup, walnuts, aspirin, shellfish, poison ivy, and chocolate.
Asthma, Chronic Bronchitis and Emphysema
Do not try to diagnose or treat yourself. Asthma, chronic bronchitis, and emphysema must be diagnosed and treated by a doctor or other health professional. Two other common conditions that cause breathing difficulties, congestive heart failure and pneumonia, have similar symptoms, and many of the drugs used to treat asthma or COPD may worsen these conditions. Therefore, it is extremely important that you have your condition properly diagnosed before starting any medication.


A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include Drug and Dietary Supplement Profiles where your selected drug is a primary subject of discussion.


Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion.

The Persistent Problem of Drug Shortages in the United States
September 2023
Worst Pills, Best Pills News often highlights expensive drugs that have limited benefits and significant health risks. At the same time, some inexpensive and highly effective drugs are in such short supply that they are being rationed. The “From the Editor” column discusses the persistent problem of drug shortages in the United States.
Important Drug Interactions for Sotalol
January 2023
Patients taking the drug sotalol (BETAPACE, BETAPACE AF, SORINE, SOTYLIZE) should be aware that it has clinically important and potentially dangerous interactions with many other prescription medications.
News Brief: Shortages in Albuterol Asthma Inhalers During the COVID-19 Pandemic
October 2020
In this month’s news brief, we report on shortages of the inhaled asthma drug albuterol that have occurred because of the coronavirus pandemic.
Drug-Induced Tremor
July 2018
Tremor is the single most common movement disorder, affecting millions of people in the U.S. If you have tremors, could one of your drugs be the cause? Read this article to learn the answer.
Update on the Long-Term Treatment Of Chronic Obstructive Pulmonary Disease
November 2015
In this article, we provide a detailed update of the various drugs available for the long-term management of chronic obstructive pulmonary disease (COPD). Learn which drugs are safest for treating COPD and which ones we have designated as Do Not Use.
Update: Treatment of Chronic Asthma
August 2015
Asthma is a common disease afflicting more than 16 million American adults and 6 million children. Find out the safest and most effective options for managing this chronic lung disease.
Steroid Treatment for COPD Exacerbations: Five Days Just as Effective as 14 Days
October 2013
If you or a loved one has chronic obstructive pulmonary disease (COPD), sometimes known as emphysema, and suffers from periodic acute COPD exacerbations requiring steroids, you should know that new research demonstrates that a five-day course of steroids for treating such exacerbations works just as well as a conventional 14-day course.
Treatment for Chronic Obstructive Pulmonary Disease
February 2013
Commonly known as emphysema, chronic obstructive pulmonary disease (COPD) affects an estimated 24 million Americans, only half of whom are diagnosed. This article presents recent information regarding the use of drug treatments, including inhaled anti-inflammatory steroids, as well as important nondrug treatments that can be used as an adjunct to drug therapy.
Smoke & Mirror Marketing (& Other Clever Big Pharma Tricks)
May 2010
The article reviews 12 prescription drugs, many of which are top-sellers, all of which are greatly overpriced in comparison to older "versions" of the same drugs. The patents on the old drugs expired so the "innovative" companies patented these new products, gaining a patent on them, and, for all practical purposes, using them as a license to print money. There is no evidence that any of the new ones are better than the now less-expensive, old versions.
Advice for Patients: New Inhaler Propellants to Replace CFC Inhalers
August 2008
With the imminent demise of CFC-propelled albuterol asthma inhalers and the substitution of HFA (hydroflouroalkane)as a more environmentally-friendly propellant, two sets of problems arise. First, and the main subject of this article, are differences between the old and new propellants that require special attention by asthmatics using the new HFA asthma inhalers because they may clog more easily than the older CFC-containing ones. The second problem is cost in that less expensive generic versions of the HFA inhalers will not be available until 2010 and the half-as-expensive generic CFC albuterol inhalers will not be manufactured or sold after December 31, 2008.
A Review of Levalbuterol (XOPENEX HFA) Inhaler for Asthma
February 2007
If you are presently using albuterol and your asthma is adequately controlled, there is no medical reason why you should be switched to levalbuterol. There is no convincing evidence that it is any safer or more effective than the older, much less expensive short-acting beta agonist, albuterol.
Selling New Drugs Using Smoke and Mirror (Images)
March 2003
You should avoid these "new" single mirror images of old drugs, not out of concern about their safety or effectiveness, but because they are the same as the old drugs. In the long run, they cause economic harm both to individuals and to the health care system because they have come on the market with extended monopoly protection. Article lists some examples.


Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion.

Letter to HHS that supports a criminal investigation of Schering-Plough based on the possibility that the company knowingly shipped millions of asthma drug inhalers that may not have contained any active ingredients. (HRG Publication #1586)
As can be seen on the chart below, there were no deaths reported to the FDA to have occurred in users of Proventil or Warrick’s albuterol (generic version also manufactured by Schering-Plough) during the first three quarters of 1998. However, starting with a death that occurred in the fourth quarter of 1998 and continuing through the second quarter of 2000, there were a total of 17 deaths for which the Schering-Plough albuterol was listed as the primary suspect and in which there is a date of death.
Request to HHS to investigate charges against Schering-Plough for possibly knowingly shipping millions of asthma drug inhalers that may not have contained any active ingredient (HRG Publication #1559)
We urge you to launch an investigation into criminal charges against Schering-Plough based on the possibility that the company knowingly shipped millions of the 59 million units of albuterol-containing asthma drug eventually recalled between the time the company became aware of the seriously flawed manufacturing processes and the time the recall was finally accomplished.