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pantoprazole (PROTONIX)


Drug and Dietary Supplement Profiles
A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion
Disease and Drug Family Information
Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • Ulcers and Gastroesophageal Reflux Disease (GERD) [hide all summaries]
    There are nondrug treatments, with no safety concerns, and less expensive drugs that may be effective for GERD; these should be tried before you use any drugs for heartburn. First, try to avoid foods that trigger your condition (e.g., fatty foods, onions, caffeine, peppermint, and chocolate), and avoid alcohol, smoking, and tight clothing. Second, avoid food, and particularly alcohol, within two or three hours of bedtime. Third, elevate the head of the bed about six inches or sleep with extra pillows.
Worst Pills, Best Pills Newsletter Articles
Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Proton Pump Inhibitors: Dangerous and Habit-Forming Heartburn Drugs [hide all summaries]
    (November 2011)
    PPIs are now one of the most widely used classes of prescription drugs, with an estimated one out of every 20 people in the developed world currently taking one of these medications. However, given that recent research shows PPIs may be habit-forming, that the majority of PPI use is probably inappropriate, with minimal or no benefit to the patient, and that new, life-threatening risks with long-term therapy are continually emerging, it is time for the medical community to re-evaluate the role of PPIs in everyday practice.
  • Interactions Between Methotrexate (TREXALL) and Proton Pump Inhibitors (PPIs) and Many Other Drugs [hide all summaries]
    (January 2011)
    This article discusses the dangerous interactions that can occur when using methotrexate (TREXALL) with certain other drugs. See our list of 27 drugs you should never take with methotrexate.
  • Possible Increased Risk of Fractures With Long-Term, High-Dose Use of Heartburn Drugs [hide all summaries]
    (August 2010)
    The article reviews evidence that patients 50 years old or older who take proton pump inhibitors (PPIs -- a list of the six approved ones is in the article) or use them for a year or more may be at increased risk of fractures of the hip, wrist and spine. Since much of the use of these drugs is inappropriate and unnecessarily dangerous, the article discusses pharmacologic and non-pharmacologic alternatives to PPIs.
  • Avoiding Overuse of Proton Pump Inhibitors (PPIs) [hide all summaries]
    (March 2008)
    This article reviews evidence for the international epidemic of overuse of proton pump inhibitors (PPI), drugs used to treat ulcers and gastroesophageal reflux disease (GERD). There were 70 million prescriptions filled in U.S. pharmacies in 2006 for the four leading PPI drugs: esomeprazole (NEXIUM), lansoprazole (PREVACID), pantoprazole (PROTONIX) and rabeprazole (ACIPHIX). Find out about several serious side effects of these drugs such as increased community-acquired pneumonia, increased hip fractures and acute kidney inflammation. Learn about alternatives to using PPIs.
Additional Information from Public Citizen
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  • Petition Urging FDA to Add Warnings to Proton Pump Inhibitors (HRG Publication #1964) [hide all summaries]
    Public Citizen petitions the FDA to immediately add black box warnings and other safety information concerning several severe risks to the product labels of all proton pump inhibitors (PPIs) presently on the market in the U.S. In addition, the serious nature of so many of these adverse reactions also mandates the requirement for FDA-approved patient Medication Guides, none of which exist now, for all of these drugs.
Health Letter Articles
Search results below include Health Letter Articles where your selected drug is a primary subject of discussion
  • Proton-Pump Inhibitors: Dangerous and Habit-Forming Heartburn Drugs [hide all summaries]
    (September 2011)
    PPIs are now one of the most widely used classes of prescription drugs, with an estimated one out of every 20 people in the developed world currently taking one of these medications. However, given that recent research shows PPIs may be habit-forming, that the majority of PPI use is probably inappropriate, with minimal or no benefit to the patient, and that new, life-threatening risks with long-term therapy are continually emerging, it is time for the medical community to re-evaluate the role of PPIs in everyday practice.

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