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morphine (AVINZA, KADIAN, MS CONTIN)

• acetaminophen and codeine (APAP, TYLENOL WITH CODEINE); acetaminophen and hydrocodone (BANCAP-HC, LORTAB, VICODIN); acetaminophen and oxycodone (PERCOCET, ROXICET, TYLOX); aspirin and oxycodone (PERCODAN); codeine; hydrocodone and ibuprofen (VICOPROFEN); hydromorphone (DILAUDID); meperidine (DEMEROL); morphine (AVINZA, KADIAN, MS CONTIN); oxycodone (OXYCONTIN)

• Narcotics [hide all summaries]
  Most of the time when someone is able to swallow, they should first try a nonnarcotic drug such as aspirin taken by mouth. If aspirin alone is not effective, it can be combined with a narcotic, such as codeine. These two drugs work in different ways, and when they are used together, they generally relieve pain that would otherwise require a higher dose of narcotic, while causing fewer adverse effects.

• Oxycodone: Be Careful What You Take With It [hide all summaries]
  (September 2009)
  The article lists 24 drugs that can increase the toxicity of oxycodone if taken together with the drug and 11 other drugs that can weaken its effectiveness as a painkiller if they are simutaneously used.
• Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease [hide all summaries]
  (April 2008)
  This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.
• A Warning about AVINZA: Updated Black Box Warning on Extended-Release Morphine Capsules [hide all summaries]
  (March 2006)
  If you are now taking Avinza or Kadian, you should ask your doctor whether another painkiller such as immediate-release morphine might be more appropriate. If you decide to continue taking Avinza or Kadian, you should be sure never to consume alcohol or chew, crush, or dissolve the capsules.
• When Drinking Alcohol Causes “Dose-Dumping” in a Widely-used Painkiller [hide all summaries]
  (September 2005)
  The Food and Drug Administration (FDA) asked the maker of the long-acting potent narcotic, or opiate, painkiller hydromorphone (PALLADONE) to remove the drug from the market because of a potentially fatal interaction with alcohol. If you are now taking Palladone, Avinza, or Kadian you should talk to your physician immediately to discuss alternative treatment.
• Drugs That Can Cause Headache From Their Overuse [hide all summaries]
  (October 2004)
  A high frequency of drug intake to manage headache pain may mean that you have a condition known as medication overuse headache (MOH). According to the International Headache Society, MOH may exist when the following criteria are fulfilled: (1) there is headache on 15 or more days a month; (2) pain characteristics are dull, and of light to moderate intensity on both sides of the head; (3) drug intake includes ergots, triptans and opioids (these drugs are discussed below) for 10 or more days per month, simple painkillers 15 days or more for a minimum of 3 months; and (4) the headache disappears after withdrawal.
• Drug Induced Psychiatric Symptoms [hide all summaries]
  (October 2002)
  This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.

• Drug Recall for morphine (AVINZA, KADIAN, MS CONTIN) reported in July 8, 2009 FDA Enforcement Report

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