doxycycline (VIBRAMYCIN)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.

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Disease and Drug Family Information

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Antibiotics [hide all summaries]
Antibiotics (drugs used to treat bacterial infections) are overwhelmingly misprescribed in the United States. Despite congressional hearings and numerous academic studies on this issue, it has become the general consensus that 40 to 60% of all antibiotics in this country are misprescribed. New studies continue to confirm the fact that a large proportion of antibiotic prescribing for both children and adults continues to be inappropriate.

Tetracyclines [hide all summaries]
Tetracyclines are rarely the antibiotics of choice to treat bacterial infections that are common in older adults. In general, tetracyclines are used to treat such infections as urethritis (inflammation of the urinary tract), prostate infections, pelvic inflammatory disease, acne, Rocky Mountain spotted fever, recurrent bronchitis in people with chronic lung disease, walking pneumonia, and other miscellaneous infections.

Worst Pills, Best Pills Newsletter Articles

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Antacid Drug Interactions [hide all summaries]
(October 2009)
Antacids can interact with a number of medications, either increasing or decreasing drug effect.

Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease [hide all summaries]
(April 2008)
This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.

The Tetracycline Antibiotic Minocycline (MINOCIN) and Benign Intracranial Hypertension [hide all summaries]
(May 2003)
Benign intracranial hypertension is, in fact, not benign at all. It is also known as pseudotumor cerebri and involves a persistent rise in cerebrospinal fluid pressure. This reaction is characterized by headache, nausea, vomiting and papilledema (a sign of increased pressure within the central nervous system) with partial paralysis of a nerve that controls eye movement and some facial muscles (sixth cranial nerve palsy). If you are taking minocycline or another tetracycline and develop a persistent unexplained headache, this should be reported to the prescribing physician immediately.

Drugs for Possible Exposure to Anthrax: What Makes Sense? [hide all summaries]
(November 2001)
With each new day come new reports of exposures, possible exposures and what turn out to be fake exposures to anthrax. Originally coming from Florida, reports are now emanating from other states including New York, Nevada and the District of Columbia.

Additional Information from Public Citizen

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Letter to the Editor of the New York Times concerning mis-statements by HHS Secretary Tommy Thompson on drugs used to treat anthrax (HRG Publication #1598) [hide all summaries]
You quote Tommy G. Thompson, the secretary of Health and Human Services, as saying doxycycline and penicillin are just as effective as Cipro (news article, Oct. 20). The major study in the field, published by United States Army researchers in 1993, does not support this statement.