doxazosin [prostate] (CARDURA [PROSTATE])

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.

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Disease and Drug Family Information

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Benign Prostatic Hypertrophy (BPH) [hide all summaries]
If your BPH symptoms are minimal, no treatment is necessary, no matter what the size of your prostate gland. If you have BPH symptoms and do not have a very enlarged gland, then an alpha-blocker such as terazosin would be the best choice. If your prostate is very enlarged, treatment with an alpha-blocker would again be the best choice. Finasteride should be used only if an alpha-blocker failed to relieve your symptoms.

Worst Pills, Best Pills Newsletter Articles

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Alpha-Blockers for Prostate Enlargement: Some Important Drug Interactions [hide all summaries]
(June 2009)
Taking alpha-blockers in combination with drugs for erectile dysfunction and with other drugs can cause dizziness and fainting. In this article we will discuss alfuzosin (UROXATRAL), doxazosin (CARDURA), tamsulosin (FLOMAX) and terazosin (HYTRIN) and drugs with which they can have harmful interactions.

Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease [hide all summaries]
(April 2008)
This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.

Internet-Sold Dietary Supplements For Erectile Dysfunction May Endanger Users [hide all summaries]
(October 2006)
The FDA analysis found that some of these products illegally contained sildenafil (VIAGRA), which is FDA-approved for erectile dysfunction. Others contained chemicals similar to sildenafil.

Older Adults Not Getting the Most Effective Drugs For High Blood Pressure [hide all summaries]
(January 2001)
“You, or at least many of your colleagues, have failed to provide optimal care to your patients with high blood pressure.” This stinging critique of physician prescribing practices starts off an editorial in the Journal of General Internal Medicine for October 2000 that commented on a Harvard Medical School study of high blood pressure in older adults that appeared in the same issue.

Additional Information from Public Citizen

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Testimony before the Food and Drug Administration's Cardiovascular and Renal Drugs Advisory Committee on a petition to relabel doxazosin (Cardura). (HRG Publication #1575) [hide all summaries]
As physicians being asked by patients to recommend drugs for the treatment of hypertension, it would be highly unlikely for you or for me, knowing what we now know, to recommend an alpha blocker such as Cardura as a first choice drug. More likely, we would relegate it to a fourth or lower choice drug, only after adequate trials of diuretics, beta blockers, or ACE inhibitors, alone and in combination, had been tried without success.