Worst Pills
pregabalin (LYRICA)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion
  • pregabalin (LYRICA)
    We list this drug as Do Not Use to treat neuropathic pain because the risks outweigh the potential benefits. We recommend that individuals Do Not Use this drug to treat epilepsy until 2012.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Pregabalin (LYRICA): Neither Effective nor Safe for Treating Sciatica Leg Pain [hide all summaries]
    (November 2017)
    Doctors often prescribe pregabalin for a neuropathic pain condition known as sciatica, a use that is not approved by FDA. Find out why pregabalin is a bad choice for treating sciatica.
  • Important Questions About Shingles [hide all summaries]
    (June 2016)
    Shingles is a very common disease caused by the chicken (herpes zoster) virus. Elderly adults are particularly vulnerable to developing this painful and sometimes debilitating condition. Learn the facts about shingles and how you can lower your risk of developing it.
  • Pregabalin (LYRICA): OK for Certain Seizures, but Not Pain [hide all summaries]
    (December 2014)
    LYRICA is heavily promoted for treatment of chronic pain due to fibromyalgia and other conditions. Learn why Public Citizen’s Health Research Group advises against using the drug to treat these painful conditions.
  • Drug-Induced Parkinsonism [hide all summaries]
    (October 2010)
    A study discovered that more than 1 out of every 10 people who went to a Parkinson’s disease center was found to have drug-induced Parkinsonism. These people were misdiagnosed as having the more common illness, Parkinson’s disease, which is irreversible and has unknown causes.
  • Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia [hide all summaries]
    (April 2009)
    This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
  • New Evidence of Suicidal Thinking and Behavior In Patients Using Anti-Epileptic Drugs [hide all summaries]
    (November 2008)
    Among patients taking antiepileptic drugs for epilepsy, the risk of suicidal thinking and behavior was 3.5 times greater compared to placebo. These drugs are also used to treat pain and as mood stabilizers in people with manic-depressive disorders. Pay attention to common warning signs that may indicate an increased risk of suicide, including: talking or thinking about hurting oneself or ending one’s life; withdrawal from family and friends; worsening depression; increased preoccupation with death and dying; giving away prized possessions. Do not make any medication regimen changes without consulting your provider. Unsupervised sudden changes in prescription drugs can have dangerous adverse effects

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