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montelukast (SINGULAIR)

• montelukast (SINGULAIR); zafirlukast (ACCOLATE)
  We list these drugs as Do Not Use drugs because they are less effective than other drugs and can cause blood vessel inflammation, liver disease, lupus and recurrences of ulcerative colitis.

• Allergy and Hayfever [hide all summaries]
  If you suffer from an itchy and runny nose, watery eyes, sneezing, and a tickle in the back of your throat, then you probably have an allergy. An allergy means a hypersensitivity to a particular substance called an allergen. Hypersensitivity means that the body’s immune system, which defends against infection, disease, and foreign bodies, reacts inappropriately to the allergen. Examples of common allergens are pollen, mold, ragweed, dust, feathers, cat hair, makeup, walnuts, aspirin, shellfish, poison ivy, and chocolate.
• Asthma, Chronic Bronchitis and Emphysema [hide all summaries]
  Do not try to diagnose or treat yourself. Asthma, chronic bronchitis, and emphysema must be diagnosed and treated by a doctor or other health professional. Two other common conditions that cause breathing difficulties, congestive heart failure and pneumonia, have similar symptoms, and many of the drugs used to treat asthma or COPD may worsen these conditions. Therefore, it is extremely important that you have your condition properly diagnosed before starting any medication.

• FDA Requires Warnings about Serious Mental and other Side Effects With Certain Asthma Drugs [hide all summaries]
  (August 2009)
  The FDA has just warned about about mood and behavior changes for three drugs used to treat asthma: montelukast (SINGULAIR), zafirlukast (ACCOLATE) and zileuton (ZYFLO, ZYFLO CR). The article describes these side effects and urges that patients talk with their health care providers if these events occur. However, we advise that patients should not stop any asthma medication without first consulting your physician. Abruptly stopping a medication may result in acutely deteriorating asthma control.
• Cutting Your Drug Bill While Reducing Your Risk Of Avoidable Adverse Drug Reactions: Six Examples [hide all summaries]
  (February 2005)
  This article will look at the potential savings for the individual consumer if the alternative treatments recommended in Worst Pills, Best Pills were used for six DO NOT USE drugs. All six are listed in the Drug Topics Magazine Top 200 selling drugs in U.S. in 2003. The drugs are: celecoxib (CELEBREX) used for arthritis and pain; the Alzheimer’s disease drug donepezil (ARICEPT); drospirenone with ethinyl estradiol (YASMIN 28), an oral contraceptive; esomeprazole (NEXIUM) the “new purple pill” for heartburn; montelukast (SINGULAIR), a drug approved for both asthma and hay fever; and valdecoxib (BEXTRA), an arthritis drug very similar to celecoxib.The combined sales of these six DO NOT USE drugs was $8.1 billion with more that 75 million prescriptions dispensed in 2003.
• DO NOT USE! Asthma Drug Montelukast (SINGULAIR) For The Treatment Of Hay Fever [hide all summaries]
  (November 2003)
  The Food and Drug Administration (FDA), on January 23, 2003, approved the asthma drug montelukast (SINGULAIR) for the relief of symptoms of seasonal allergic rhinitis (hay fever) in adults and children two years of age and older. Montelukast is a member of a family of drugs known as leukotriene inhibitors.You should not use montelukast for the treatment of hay fever symptoms because of its meager effectiveness and exorbitant cost.

• Drug Recall for montelukast (SINGULAIR) reported in June 24, 2009 FDA Enforcement Report
• Drug Recall for montelukast (SINGULAIR) reported in June 17, 2009 FDA Enforcement Report

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