Search Type: drug or dietary supplement name
Search Term: omeprazole (PRILOSEC, PRILOSEC OTC)


Worst Pills, Best Pills Newsletter Articles

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • Combination Treatments for Helicobacter Pylori Infection [hide all summaries]
    The bacterium Helicobacter pylori (H. pylori) has been implicated in causing ulcer disease. The combination treatments described have high success rates and low recurrence rates, but the treatment is arduous.
  • Ulcers and Gastroesophageal Reflux Disease (GERD) [hide all summaries]
    There are nondrug treatments, with no safety concerns, and less expensive drugs that may be effective for GERD; these should be tried before you use any drugs for heartburn. First, try to avoid foods that trigger your condition (e.g., fatty foods, onions, caffeine, peppermint, and chocolate), and avoid alcohol, smoking, and tight clothing. Second, avoid food, and particularly alcohol, within two or three hours of bedtime. Third, elevate the head of the bed about six inches or sleep with extra pillows.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Proton Pump Inhibitors Linked to Dementia in the Elderly [hide all summaries]
    (August 2016)
    In this article, we review new research linking use of the heartburn and ulcer medications known as proton pump inhibitors to an increased risk of dementia.
  • Proton Pump Inhibitors Might Cause Chronic Kidney Disease [hide all summaries]
    (July 2016)
    Public Citizen's Health Research Group has long warned about the serious risks of the commonly used group of heartburn drugs known as proton pump inhibitors. In this article, we discuss new research suggesting that chronic kidney disease is another potential side effect of these drugs.
  • Antibiotics, Common Heartburn Drugs And Spread of Potentially Fatal Intestinal Infection [hide all summaries]
    (August 2015)
    Proton pump inhibitors, a widely used class of heartburn drugs, and essentially all antibiotics increase your risk of C. difficile infections, which can cause severe, even life-threatening diarrhea illness. Read this article to find out how to protect yourself from this dangerous infection.
  • With Some Drugs, Crushing Tablets Or Opening Capsules Could Have Fatal Consequences [hide all summaries]
    (February 2015)
    Patients who have difficulty swallowing pills will sometimes crush tablets or open capsules and sprinkle the resulting powder, fragments or granules into food or liquids. Other patients will resort to chewing their pills before swallowing. Find out the dangers posed by taking such measures.
  • New Warnings on Common Heartburn Drugs: Too Little — and, for Some, Too Late [hide all summaries]
    (February 2015)
    After a more than three-year delay and a Public Citizen lawsuit filed against the FDA, the agency finally responded to our petition for stronger label warnings on a class of medications, known as proton pump inhibitors, commonly used to treat heartburn. This article discusses the new warnings that the FDA has required in response to our petition.
  • Update on Grapefruit Juice-Drug Interactions [hide all summaries]
    (July 2012)
    This article updates and expands our earlier list of drugs that can have harmful interactions with grapefruit juice. The list now includes 82 different drugs.
  • Proton Pump Inhibitors: Dangerous and Habit-Forming Heartburn Drugs [hide all summaries]
    (November 2011)
    PPIs are now one of the most widely used classes of prescription drugs, with an estimated one out of every 20 people in the developed world currently taking one of these medications. However, given that recent research shows PPIs may be habit-forming, that the majority of PPI use is probably inappropriate, with minimal or no benefit to the patient, and that new, life-threatening risks with long-term therapy are continually emerging, it is time for the medical community to re-evaluate the role of PPIs in everyday practice.
  • Interactions Between Methotrexate (TREXALL) and Proton Pump Inhibitors (PPIs) and Many Other Drugs [hide all summaries]
    (January 2011)
    This article discusses the dangerous interactions that can occur when using methotrexate (TREXALL) with certain other drugs. See our list of 27 drugs you should never take with methotrexate.
  • Possible Increased Risk of Fractures With Long-Term, High-Dose Use of Heartburn Drugs [hide all summaries]
    (August 2010)
    The article reviews evidence that patients 50 years old or older who take proton pump inhibitors (PPIs -- a list of the six approved ones is in the article) or use them for a year or more may be at increased risk of fractures of the hip, wrist and spine. Since much of the use of these drugs is inappropriate and unnecessarily dangerous, the article discusses pharmacologic and non-pharmacologic alternatives to PPIs.
  • Dexlansoprazole (KAPIDEX, DEXILANT): The Sixth Proton Pump Inhibitor for Heartburn [hide all summaries]
    (July 2010)
    This sixth drug for treating "heartburn" has no advantage for patients over older drugs such as PREVACID, generic name lansoprazole. Any advantage is for the industry because the manufacturer of DEXILANT charges three times more for this drug than the cost of generic lansoprazole, sold by another company and just as effective for patients.
  • Smoke & Mirror Marketing (& Other Clever Big Pharma Tricks) [hide all summaries]
    (May 2010)
    The article reviews 12 prescription drugs, many of which are top-sellers, all of which are greatly overpriced in comparison to older "versions" of the same drugs. The patents on the old drugs expired so the "innovative" companies patented these new products, gaining a patent on them, and, for all practical purposes, using them as a license to print money. There is no evidence that any of the new ones are better than the now less-expensive, old versions.
  • Antacid Drug Interactions [hide all summaries]
    (October 2009)
    Antacids can interact with a number of medications, either increasing or decreasing drug effect.
  • Avoiding Overuse of Proton Pump Inhibitors (PPIs) [hide all summaries]
    (March 2008)
    This article reviews evidence for the international epidemic of overuse of proton pump inhibitors (PPI), drugs used to treat ulcers and gastroesophageal reflux disease (GERD). There were 70 million prescriptions filled in U.S. pharmacies in 2006 for the four leading PPI drugs: esomeprazole (NEXIUM), lansoprazole (PREVACID), pantoprazole (PROTONIX) and rabeprazole (ACIPHIX). Find out about several serious side effects of these drugs such as increased community-acquired pneumonia, increased hip fractures and acute kidney inflammation. Learn about alternatives to using PPIs.
  • Over-The-Counter Omeprazole (PRILOSEC OTC) — There Are Better Choices For Heartburn [hide all summaries]
    (October 2003)
    You should try the non-pharmacologic interventions listed in the box below before trying antacids, histamine-2 blockers, or, as a last resort, proton pump inhibitors. If you classify yourself as a person with frequent heartburn, that is heartburn more than two days per week, and the interventions recommended above have failed, you should be under the care of a physician
  • Selling New Drugs Using Smoke and Mirror (Images) [hide all summaries]
    (March 2003)
    You should avoid these "new" single mirror images of old drugs, not out of concern about their safety or effectiveness, but because they are the same as the old drugs. In the long run, they cause economic harm both to individuals and to the health care system because they have come on the market with extended monopoly protection. Article lists some examples.
  • Grapefruit Juice and Drug Interactions [hide all summaries]
    (June 2002)
    Grapefruit juice can interact with a number of therapeutically important drugs that could lead to the possibility of toxicity. These drugs are listed in the article.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • Petition Urging FDA to Add Warnings to Proton Pump Inhibitors (HRG Publication #1964) [hide all summaries]
    Public Citizen petitions the FDA to immediately add black box warnings and other safety information concerning several severe risks to the product labels of all proton pump inhibitors (PPIs) presently on the market in the U.S. In addition, the serious nature of so many of these adverse reactions also mandates the requirement for FDA-approved patient Medication Guides, none of which exist now, for all of these drugs.

Health Letter Articles

Search results below include Health Letter Articles where your selected drug is a primary subject of discussion
  • Proton-Pump Inhibitors: Dangerous and Habit-Forming Heartburn Drugs [hide all summaries]
    (September 2011)
    PPIs are now one of the most widely used classes of prescription drugs, with an estimated one out of every 20 people in the developed world currently taking one of these medications. However, given that recent research shows PPIs may be habit-forming, that the majority of PPI use is probably inappropriate, with minimal or no benefit to the patient, and that new, life-threatening risks with long-term therapy are continually emerging, it is time for the medical community to re-evaluate the role of PPIs in everyday practice.

SHOW secondary search results for omeprazole (PRILOSEC, PRILOSEC OTC)

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